Tang Dingzhong team and Zhou Jianmin team published a review of "Plant Immune Signals: Two Frontier Research Advances"

Recently, jipb published online on Wiley website "plant immune signaling: improving on two frontiers" by Tang Dingzhong and Zhou Jianmin from Institute of genetics and developmental biology, Chinese Academy of Sciences.this review summarizes the latest achievements in the field of plant immunity, especially discusses the activation mechanism of PRRS on the surface of plant cell membrane and NLRs protein, dynamic regulation and molecular mechanism of activating downstream immune signals.in this review, the future development trend and challenges in the field of plant immunity were also prospected.plants will be invaded by a variety of pathogenic microorganisms in the whole process of growth and development.in order to resist the invasion of pathogens, plants have evolved two levels of innate immune system.the first level is the PTI immune response triggered by the conservative related molecular mode of pathogens; the second level is the ETI immune response triggered by pathogen effector factors.immune receptor proteins play an indispensable role in the production and transmission of immune signals at these two levels.when pathogens invade, PRRS, which are located on the surface of plant cell membrane, can quickly recognize the conserved components of the pathogen itself and produce a series of immune responses, such as activation of MAPKs cascade signal pathway, activation of calcium dependent protein kinase cpks pathway, outbreak of reactive oxygen species (ROS) and closure of stomata Ti immune response.in this process, the activation and dynamic regulation of PRRS proteins are the key to immune signal generation.at the same time, in order to transmit immune signals, PRRS proteins need to form complexes with downstream acting elements (such as intracellular cytoplasmic receptor like kinase rlcks, etc.).recent research progress has directly linked the production of many PTI reactions with PRRS complexes. This review describes the molecular mechanism of these reactions in detail.in order to inhibit the PTI immune response of plants, some pathogens can secrete effector factors into host cells to make plants susceptible.facing the invasion of pathogens, plants have evolved NLRs, which can recognize effector factors, and activate a stronger immune response, namely ETI immune response.NLRs can be divided into three groups according to their N-terminal variable domains: CNLS, tnls and RNLS.recently, great breakthroughs have been made in the study of NLRs.for example, for the first time, we successfully analyzed the structure of plant full-length CNL protein ZAR1; for the first time, it was found that tnls protein induced programmed cell death depended on NAD + enzyme activity of TIR domain; in addition, NRG1 and ADR1 of RNLS were identified as helper proteins to participate in tnls and CNLS mediated ETI reaction. These important findings were discussed in detail in this review.Dr. Wang Wei of Tang Dingzhong team is the first author of the paper, Professor Feng Baomin of plant immunity center of Fujian agriculture and Forestry University participated in the writing of the paper, and Professor Tang Dingzhong and researcher Zhou Jianmin are co authors. the project is supported by the National Natural Science Foundation of China. official account of the most advanced plant science is the most popular official account in the field of Botany. In order to better promote the exchange of subjects, we have created 100 vertical subdivision discussions, covering 20000 active users directly. You can quickly consult your colleagues for professional questions and get answers. Currently, there are discussions in the following fields: gene family / genome editing / population genetics. Science / hormone / proteomics / transcriptomics / metabonomics / synthetic biology / plant and pathogen interaction / medicinal plants / digital agriculture / bryophytes / epigenetics / root microorganism / light signal transduction / plant tissue culture / experimental technology protein / experimental technology gene / non coding RNA / single cell sequencing / molecular marker assisted breeding / Plant Germplasm Resources / coarse grain breeding / crop cultivation / flower Huihe and ornamental plants / plant protection - insects / cell biology / postharvest biology / plant evolution / plant transgenic technology / plant nutrition / heterosis / ecology / more research direction groups are being formed... If you want to join us, please scan the QR code to add friends, and then pay attention to the information of friends circle to know how to join the group In addition to the latest advances in plant science, monographs are devoted to the publication of information, recruitment information and sharing of methods and software. for submission and recruitment, please reply "contribution" from the background, which is free of charge; for business cooperation, please contact wechat ID: zwkxqy;