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IgG4-related disease (IgG4-RD) is a chronic autoimmune disease, a chronic fibroinflammatory autoimmune disease with multisystem involvement
immunity
To date, no meta-analysis has assessed the risk of malignancy in IgG4-RD
A total of 10 studies were included in this paper
Meta-analysis results
All studies reported overall SIR for malignancies
diagnosis
Patients with IgG4-RD had an increased risk of malignancy (SIR = 2.
I 2 Pancreatic cancer 3 Lymphoma 3Stomach cancer 3 Lung cancer 3
To further understand sources of heterogeneity, subgroup analyses were performed by study quality, geographic region, and mean follow-up time (Table 2)
[6], Ahn[3] [10] , I 2 0%, P Statistics P P , P Management Screening
Original source:
Tingfeng Yu , et al.
Tingfeng Yu Arthritis Res Ther.
Arthritis Res Ther.
Published online 2022 Jan 5.
doi:10.
1186/s13075-021-02652-2 10.
1186/s13075-021-02652-2Leave
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