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Taking a single tablet of compound preparation to lower blood pressure has 3 major advantages!
Author: meilin
Located in: Health Encyclopedia
However, the food was so good that I was dumbfounded by the time of the physical examination, and high blood pressure had come to my door unknowing.
Moreover, if hypertension is not well controlled, it will cause serious complications such as heart failure, renal failure, myocardial infarction, cerebral infarction, and cerebral hemorrha.
Over 20 years of high blood pressure without complications
How did Academician Zhong Nanshan do it?
The 85-year-old academician Zhong Nanshan once revealed in an interview that he has suffered from high blood pressure for more than 20 yea.
But he looks full of ener.
How did Zhong Lao do it? He has suffered from high blood pressure for so many years without complications?
[Image source: Xiamen Evening News]
Zhong Lao said that high blood pressure is not terrib.
As a model representative of hypertensive patients, .
Keep exercising
Zhong Lao once said: "Exercise is like eati.
Studies have shown that exercise can help repair damaged blood vessels in hypertensive patients, reduce oxidative stress, slow down lipid deposition in blood vessel walls, repair blood vessel damage caused by hypertension, enhance substance metabolism, and prevent and treat hypertensi.
However, patients with high blood pressure are not suitable for vigorous exerci.
Eat a healthy diet
The daily diet of hypertensive patients should pay attention to the principles of low salt, low fat and low calorie, especially sa.
The dietary guidelines for Chinese residents recommend that the daily intake of salt is less than 6 grams, which is about as much as the cap of a beer bott.
Get enough sleep
Zhong Lao once said in an interview that he must go to bed after eleven o'clock in the evening, get up at seven in the morning, and take a nap for half an hour at no.
Sleeping well and not staying up late can make blood pressure more stab.
Therefore, hypertensive patients must adjust their living habi.
However, in clinical practice, many hypertensive patients need combined treatment, resulting in a lot of medicines and complicated drugs, and it is difficult for patients to adhere to it for a long ti.
SPC antihypertensive drugs
"Lower blood pressure" treasure for hypertensive patients
SPC, consisting of two or more drugs with different antihypertensive mechanisms, is an optimization and extension of combination therapy that has been used in the treatment of hypertension for more than 50 yea.
Compared with traditional antihypertensive drugs, it mainly has the following advantages:
Good effect and few adverse reactions
The synergistic effect of SPC can increase the efficacy, has the advantage of reaching the target as soon as possible, and can also prevent compensatory adverse reactions that may be triggered when monotherapy lowers blood pressu.
Combination medication reduces the respective doses of the drugs, reduces the adverse reactions of the drugs, increases the safety of the drugs, and can offset or reduce the adverse reactions of the drugs [
For example, lisinopril + hydrochlorothiazide single-tablet combination
Lisinopril can improve left ventricular function and delay kidney damage while reducing blood pressure; hydrochlorothiazide can reduce blood pressure by excreting natriuresis and reducing blood volume, and can also enhance the antihypertensive effect of lisinopril [
The two synergistically strengthen blood pressure reduction, and at the same time reduce the adverse reactions of hyperkalemia, renal injury and orthostatic hypotension caused by ea.
Good compliance
SPC can reduce the types of drugs, and the antihypertensive effect of SPC is better than that of single drug and free combination drug, the rate of blood pressure reaching the standard is higher, and the time to reaching the standard is earli.
For example, a single-piece compound preparation of bisoprolol + amlodipine can control blood pressure and heart rate stably for 24 hours by taking only one tablet a d.
"One piece of medicine can make blood pressure reach the target", this experience greatly reduces the psychological burden of patients, making it easier to adhere to long-term medicati.
Control your heart rate
High blood pressure can damage blood vessels and cause atherosclerosis, which increases the burden on the heart and increases the risk of coronary heart disea.
According to data from the World Health Organization, about 17 million people worldwide die of cardiovascular disease every year, of which 4 million die from complications of hypertensi.
At least 45% of heart disease deaths and 51% of strokes are caused by high blood pressu.
Therefore, while controlling blood pressure, hypertensive patients should also pay attention to controlling heart ra.
Among many SPC antihypertensive drugs, bisoprolol + amlodipine single-piece compound preparation can stabilize blood pressure and heart rate at the same ti.
Amlodipine can inhibit the production of vascular smooth muscle, reduce blood pressure and resistance of peripheral blood vessels, reduce calcium load, improve the function of vascular endothelial cells in vivo, reduce the occurrence of cardiovascular diseases, and protect the heart muscle of patien.
【5】
Bisoprolol has strong selectivity for beta-adrenergic receptors, which can help to slow down the patient's heart rate, weaken the patient's myocardial contractility, and then reduce the patient's cardiac output, so that the patient can obtain myocardial protection during rehabilitati.
【6】
The combination of the two can help patients stabilize blood pressure faster and reduce the risk of coronary heart disease and chronic heart failure while reducing adverse reactio.
However, there are many types of antihypertensive drugs for SPC, and the antihypertensive mechanisms are differe.
Everyone's constitution and course of disease are also differe.
What medicine to take and how to take it must be decided under the guidance of a doct.
Editor: Pang Siqin
Drawing: Aliao
Produced by: "Chinese Family Doctor" magazine
References:
[1] Jing Huife.
Research progress on exercise, hypertension and vascular endothelial cell growth factor [.
Journal of Yan'an University, 2015, 34(3): 109-11
[2] Li Xue, Chen Guiying, Zhang Miaomiao, e.
"Relationship between brain function indicators and sleep quality in patients with essential hypertension" [.
Chinese General Medicine, 2020-13
[3] Du Xiaofeng, Xu Nantu, Long Xueyu.
New progress in research on single-piece compound antihypertensive preparations [J];Modern Medicine and Health, V.
31, Issue 10, May 30, 2015
[4] Huang Di, Ding Likun, Ding Li, et .
Human pharmacokinetics of compound lisinopril tablets [.
Chinese Journal of Pharmacy, 2002(43,4):304-30
[5] Liao Zhixio.
Efficacy study of bisoprolol combined with amlodipine in the treatment of elderly patients with coronary heart disease and hypertension; Medical Journal of the Ministry of Equipment; 2019-03
[6] Cai Chao, Chen Zhen, Wang Chongquan, Wang Zhixiao, Mao Shan, Chen Xiaoqia.
Effects of amlodipine and bisoprolol on CAP and IMT in hypertensive patients with angina pectoris [.
Advances in Modern Biomedicine, 2016, 16(18 ): 3530-3532+353
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