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Chemotherapy-induced peripheral neuropathy (CIPN) refers to sensory or motor disturbances in the extremities caused by direct damage to the peripheral nervous system by chemotherapy drugs
Chemotherapy-Induced Peripheral Neuropathy (CIPN) Determines Effective CIPN Treatment As a traditional Chinese medicine (TCM) therapy, Chinese herbal medicine (CHM) has unique advantages in improving clinical symptoms, improving chemotherapy efficacy, and reducing its side effects
Document identification and screening flowchart :
Methods: Relevant RCTs and RCTs for CHM external treatment of CIPN were searched and evaluated in 9 electronic databases including China National Knowledge Base Database, China Biomedical CD-ROM, China Science and Technology Journal Database, Wanfang Database, PubMed, Cochrane Library, MEDLINE, and Web of Science.
method:
Basic information for included articles :
Basic information for included articles :Results: According to the inclusion and exclusion criteria, 33 clinical studies were included, and 1354 studies were screened
result:
CIPN is characterized by pain and numbness in the limbs, which Chinese medicine calls "bi syndrome"
The basic principles of Chinese medicine treatment of "arthralgia" should focus on invigorating qi, nourishing blood, promoting blood circulation, and dredging collaterals.
The external treatment of CHM is based on the theory of meridians and collaterals, which can enhance the penetration of drugs into the body through the skin.
Traditional Chinese medicine treatment of CIPN has preventive and control effects by reducing the incidence of peripheral neurotoxicity, alleviating clinical symptoms, and improving quality of life.
External treatment of traditional Chinese medicine is an effective method for the treatment of CIPN, which can significantly improve the clinical symptoms and quality of life of patients with CIPN.
Original text: Li QY, Cai FH, Lu Y, Liu H, Wang X, Li FL, Shi J.
Original text: Li QY, Cai FH, Lu Y, Liu H, Wang X, Li FL, Shi J.
External Treatment With Chinese Herbal Medicine for Chemotherapy-Induced Peripheral Neuropathy: A Systematic Review and Meta-Analysis.
Front Pharmacol.
2022 Feb 18 ;13:764473.
doi: 10.
3389/fphar.
2022.
764473.
PMID: 35250555; PMCID: PMC8894889.
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