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Survival prognosis for glial sarcoma is associated with MGMT promoter methylation and temozolomide

 Last Update: 2022-09-14
 Source: Internet
 Author: User

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Vasileios K.

——Excerpt from the article chapter

【Ref: Kavouridis VK, et al.

Research background

Gliosarcoma (gliosarcoma), which accounts for about 2% of glioblastoma (GBM), is an uncommon subtype of glioblastoma whose histological characteristics consist of

The authors searched the National Cancer Database for patients

Research results

A total of 580 newly diagnosed patients with glial sarcoma had MGMT status, of which 33.

Conclusions of the study

In summary, the study found that the methylation rate of the MGMT promoter of glial sarcoma is about 1/3, which is lower

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