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The muscle cells of patients with type 2 diabetes have a destroyed biological clock
Almost all cells regulate their biological processes within 24 hours, which is also called the circadian rhythm of cells
Scientists already know that when our biological clock breaks down due to shift work or sleep disorders, our metabolic health may be affected
Now, an international team of scientists has shown that the skeletal muscles of patients with type 2 diabetes have different circadian rhythms
May help fine-tune treatment time
Professor Juleen R.
They conducted further experiments using clinical trial data from type 2 diabetes patients and mice, and cell-based experiments
Some of the most widely used type 2 diabetes medications affect mitochondria, which means that the role of mitochondria may vary depending on the time of administration
Exercise and diet can affect time
"Exercise and diet are common therapeutic interventions used by patients with type 2 diabetes.
Original search:
" Disrupted circadian oscillations in type 2 diabetes are linked to altered rhythmic mitochondrial metabolism in skeletal muscle .
