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Study of CHO cell culture amplification in large bioreactors

 Last Update: 2022-09-14
 Source: Internet
 Author: User

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When performing scale-up culture of mammalian cells, key factors such as material mixing time, oxygen transfer coefficient, and carbon dioxide removal rate need to be considered

First, mixed experiments (cell-free)

The increase in the volume of liquid in the bioreactor under the batch fermentation of feeds makes mixing of materials in large volumes a challenge

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