Study finds aspirin does not reduce risk of non-obstructive coronary artery disease

Coronary artery disease is the most common type of heart disease, affecting about 6.

Non-obstructive coronary artery disease occurs when the coronary arteries narrow by less than 50%, which is caused by the formation of plaque

Statins are often prescribed for patients diagnosed with non-obstructive coronary artery disease

"In looking at nature, our data questioned the value of coronary CT angiography in the diagnosis of non-obstructive coronary artery disease after initiation of aspirin therapy," said study author Jonathan Leipzig, MD, professor and department leader at the University of British Columbia in Vancouver.

In this study, researchers used data from the CONFIRM (Coronary CT Angiography Clinical Outcomes Assessment: An International Multicenter) registry, a large, multinational database of patients undergoing CCTA

Of the patients included in the study, a total of 3571 (56%) had no plaque and 2815 (44%) had non-obstructive coronary artery disease

Baseline use of aspirin and statins was recorded in both groups

"Our findings build on previous analyses of the CONFIRM registry with 2.

Neither aspirin nor statin therapy improved clinical outcomes in patients with undetectable plaques

"Ultimately, further research is needed to determine whether clinicians should consider prescribing aspirin in patients diagnosed with non-obstructive coronary artery disease on coronary CT angiography, and at what threshold,

Journal References :

1. Praveen Indraratna, Christopher Naoum, Sagit Ben Zekry, Heidi Gransar, Philipp Blanke, Stephanie Sellers, Stephan Achenbach, Mouaz H.

   
   

2. Arzu Canan, Ann Marie Navar.