Study: Down syndrome patients have genes to suppress cancer

the latest findings from geneticists at Johns Hopkins University School of Medicine in the United States that people with Down syndrome have genes that suppress cancer, making them far less likely to develop cancer than normal people, while those who have the effect of suppressing cancer are those who were thought to promote cancer productionThe findings were published In the January 3 issue of the journal NatureDown syndrome, or Mongolian disease, 21 three bodies, called congenital fools, is one of the most common serious birth defectsPatients are caused by congenital chromosomal abnormalities, and most patients' 21st chromosomes are genetically divided by errors, causing the nucleus to contain extra chromosomes; A normal person has two genetic copies of chromosome 21, while in patients with Down syndrome there are three copiesExperiments in mice found that mice with chromosome 3 similar to Down syndrome rarely developed colon cancer in mice that were equally susceptible to colon cancer, and thattumorsmuch smaller than other miceThe result was a gene called Ets2 on chromosome 21, in which patients with Down syndrome produced a copy of the Ets2 gene more than normal, but inhibited the production of cancerAmazingly, if it weren't for Down's syndrome, it's unlikely that one more copy of the Ets2 gene, which has long been considered cancer-causing rather than cancer-suppressing, would have been found to be cancer-suppressingResearchers are now trying to find out the relationship between the Ets2 gene and other types of cancer, and are trying to develop drugs that promote the Ets2 gene in the human bodyIf the study is successful, people can use drugs to fight cancer without having Down syndromeWhile there is still a long way to go on the road to new drugs, patients with Down syndrome now offer everyone the possibility of reducing the incidence of cancer