Studies have shown that impaired kidney function is associated with cognitive impairment

Summary:

• In an analysis of data from the Framingham Heart Study, proteinuria (a hallmark of kidney disease) was associated with signs of asymptomatic stroke, and patients with proteinuria were at higher
  risk of developing mild cognitive impairment or dementia.
  

• Chronic kidney disease is not associated with markers of asymptomatic stroke, but is associated
  with a higher risk of developing dementia.
  

• The results will be presented
  at ASN Kidney Week from November 3 to November 6, 2022.
  

New research demonstrates a link between
kidney disease and the development of cognitive problems.
The results will be presented
at ASN Kidney Week from November 3 to November 6, 2022.

The study is based on data
from the population-based Framingham Heart Study.
Of the 2738 participants without dementia, 187 (7%) had chronic kidney disease and 251 (9%) had proteinuria, a urological marker of
kidney disease.
Proteinuria is associated with signs of asymptomatic stroke, and patients with proteinuria have a 65%
higher risk of mild cognitive impairment or dementia.
Chronic kidney disease was not associated with markers of asymptomatic cerebrovascular disease, but was associated with
a 51% increased risk of dementia.

"Our findings highlight the importance of proteinuria as a cerebrovascular and cognitive risk factor and suggest that there may be other common disease mechanisms in the kidneys and brain besides hypertension," said
corresponding author Dearbhla Kelly, MBBChBAO, MSc, M.
S.
, PhD, St James's Hospital Dublin.

Study: "Relationship between impaired renal function and cerebral small vessel disease and cognitive impairment: findings from the Framingham Heart Study"

ASN Kidney Week 2022 is the largest nephrology conference of its kind and will provide a forum for nephrologists and other kidney health professionals to discuss the latest research findings and participate in educational sessions
related to advances in the care of patients with kidney disease and related conditions.

Since 1966, ASN has led the fight
to prevent, treat and cure kidney disease worldwide by educating health professionals and scientists, advancing research and innovation, disseminating new knowledge, and advocating for the highest quality care for patients.
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