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On August 20, the Center for Brain Science and Intelligent Technology Excellence and Innovation of the Chinese Academy of Sciences (Neuroscience Research Institute), The Shanghai Brain Science and Brain Research Center, the National Key Laboratory of Neuroscience, the Jiuting Non-Human Primate Research Platform, and the Liang Zhifeng Research Group published their research paper "Baby in the Family promoting algeque algeque behavior" online onCurrent Biology.
The study, by creating a new experimental paradigm for objectively evaluating the alitism of macaques, combined with functional magnetic resonance imaging of sober macaques, found that in macaque families with infants, the rescue of algae behavior by macaque parents increased;
this study provides an ideal model of non-human primates studying family al-Albidity, which is conducive to exploring the neural mechanisms of al-Alto behavior.
Al-Alism is a voluntary, beneficial to other individuals, but there is no benefit to themselves or even pay a price of an act, widely exists in human society, the ancient "road uneven, pull the knife to help" of the grand chivalrous, "Ande Guangsha tens of millions of rooms, the world's cold people are happy" beautiful vision, there are nearly "helpful", "honest and friendly" teaching.
in some diseases, such as autism and antiseismal personality disorders, people tend to exhibit a certain degree of albiopathic abnormalities, so studying the neural mechanisms of alitism may provide new treatment ideas for these diseases.
Due to the lack of suitable model animals, previous studies mainly focused on humans as experimental objects, but also a small number of studies on rodents as experimental objects, the former can not carry out invasive operation to study neural loop problems, while the latter's weak social, less social activities, single behavior patterns, there are drawbacks.
as a highly socialized non-human primate (Figure A), macaques have characteristics such as monogamous family structure similar to those of humans and the common care of offspring, and social behaviors such as food sharing, mutual help and pacification exist among macaques.
suggest that macaques may be the ideal animal model for studying al-Alism.
, the researchers used macaques as model animals to establish an experimental paradigm based on rescue behavior (Figure B).
The paradigm imprisons a macaque in an "island" surrounded by water, and the other macaque on the shore, as a potential rescuer, needs to overcome the difficulties and jump into the "island", opening the door and releasing the captive to return it to safety.
Through this paradigm, the researchers found that in macaque families with infants, family members (parents, brothers and sisters) were motivated to rescue babies, but if they replaced the baby with food, the macaques did not jump into the island, suggesting that the act of rescuing the baby was purposeful and even more motivated than obtaining food.
The act of rescuing the baby decreases with the age of the baby, and when the young macaque grows to two months of age, the parents of the macaque do not jump into the island to carry out the rescue act at all;
of the above rescues are found only in macaque families with infants, and few similar rescues are found in macaque families without infants.
, babies in the family promote al-alism in macaques.
The researchers used functional magnetic resonance imaging to find that when parents of macaques with infants in their families heard baby calls (as opposed to disrupted babies), their brain regions, such as the hearing cortical and island cortical cortical layers, were specifically activated (Figure E), while adult macaques without infants in the family were not significantly activated in those areas, suggesting that these brain regions may be associated with al-Alism.
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