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On September 7, Stadson BioPharma Inc.
announced that its wholly-owned subsidiary, Staidson BioPharma Inc.
(California Biotech Co.
, Ltd.
) (hereinafter referred to as “Sureth California” or the “Company”) has received American Food and Drugs.
The FDA's notification email agrees that STSA-1005 injection will be used for the treatment of severe COVID-19 in clinical trials for the treatment of severe COVID-19 indications
.
Granulocyte-macrophage colony stimulating factor (GM-CSF) is a hematopoietic growth factor that stimulates the survival of granulocytes and monocytes by binding to the GM-CSF receptor (GM-CSFR or GMR) on the cell membrane.
Proliferation and activation, GMR is composed of specific ligand binding to the α chain (GM-CSFRα/GMRα) and signal transduction β chain (GM-CSFRβ/GMRβ)
.
STSA-1005 specifically binds to human GMRα and blocks its interaction with the ligand GM-CSF, thereby negatively regulating the innate immune response
STSA-1005 injection is independently developed by the company's wholly-owned subsidiary Stadson BioPharma Inc.
This new drug clinical trial license is the first clinical trial license for STSA-1005 injection in the world