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Patients with mild cognitive impairment may be at higher risk for stroke, but the impact of intensive blood pressure control on this effect is unclear
In a post hoc analysis of the Systolic Blood Pressure Intervention Trial (SPRINT), a post-hoc analysis of the Montreal Cognitive Assessment Baseline Score of 19 to 25 was included in a study published in Stroke, the leading journal in cardiovascular disease.
The primary outcome of the study was stroke (ischemic stroke and hemorrhagic stroke) during follow-up
We included 5091 patients (mean age 68.
CONCLUSIONS: Although the SPRINT trial failed to find that intensive blood pressure control reduced the risk of stroke in all subjects, those with Montreal Cognitive Assessment scores consistent with mild cognitive impairment were associated with a reduction in intensive blood pressure control at baseline.
Although the SPRINT trial failed to find that intensive blood pressure control reduced the risk of stroke in all participants, those with Montreal Cognitive Assessment scores consistent with mild cognitive impairment were associated with reduced risk of stroke events at baseline with intensive blood pressure control.
Original source:
Adam de Havenon.
