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Aging is associated with a chronic low-grade inflammatory state
myocardial infarction stroke
HIBISCUS-STEMI (patient cohort of biological and imaging markers of cardiovascular outcomes in ST-segment elevation myocardial infarction) and HIBISCUS-STROKE (patient cohort of biological and imaging markers of cardiovascular outcomes in stroke) are 2 cohorts The study recruited patients with STEMI who underwent percutaneous coronary intervention at the Lyon Cardiac Intensive Care Unit from 2016 to 2019 and AIS patients who underwent mechanical thrombectomy
thrombus
In both cohorts, we measured CRP (C-reactive protein), IL (interleukin)-6, IL-8, IL in serum collected from subjects at 5 time points using enzyme-linked immunosorbent assays .
immunity
A total of 260 STEMI patients and 164 AIS patients were included in the study
In both cohorts, older patients had higher levels of IL-6 and sTFN -RI in the first 48 hours, which correlated with lower lymphocyte counts and higher neutrophil-to-lymphocyte ratios related
In both cohorts, older patients had higher levels of IL-6 and sTFN-RI in the first 48 hours, which were associated with lower lymphocyte counts and higher neutrophil-to-lymphocyte ratios
Original source:
Thomas Bochaton.
