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Stroke: Kawasaki disease may increase the risk of cerebrovascular disease

 Last Update: 2021-12-25
 Source: Internet
 Author: User

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Previous exploration Kawasaki disease (KD) and cerebral vascular association between disease epidemiology come to conflicting results
.

Blood vessel

Recently, a research article was published in Stroke, an authoritative journal in the field of cardiovascular diseases.
Researchers analyzed the association between KD and cerebrovascular diseases through a population-based retrospective cohort study, and the study tested that KD may be a follow-up Hypothesis of risk factors for cerebrovascular disease
.

Researchers collected KD (n=8467) children (0-18 years old) data from the Taiwan National Health Insurance Research Database
.

Starting from the first year of observation (the baseline year), the researchers collected clinical data on each child with KD, and randomly selected 4 non-KD patients with matching gender, urbanization level of residence, and parental occupation , Formed a cohort of non-KD children (n=33868) for the analysis of the study

child

Researchers found that the overall incidence of cerebrovascular disease in the KD cohort was 3.
19 times higher, which was significantly higher than that in the non-KD cohort (14.
73 vs.
4.
62 people per 100,000 visits per year), and the overall risk of cerebrovascular disease was still higher in the KD cohort ( The adjusted hazard ratio was 3.
16 [95% CI 1.
46-6.
85])
.

In addition, in the KD cohort, children under 5 years of age had a significantly higher risk of subsequent cerebrovascular disease (adjusted hazard ratio was 3.

Thus, this nationwide retrospective cohort study shows that KD may increase the risk of subsequent cerebrovascular diseases, especially those with KD younger than 5 years old
.

This nationwide retrospective cohort study showed that KD may increase the risk of subsequent cerebrovascular diseases, especially those with KD younger than 5 years old
.

Original source:

Chien-Heng Lin.

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