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    Home > Active Ingredient News > Study of Nervous System > Stroke: How to accurately evaluate changes in intracranial hematoma?

    Stroke: How to accurately evaluate changes in intracranial hematoma?

    • Last Update: 2020-07-16
    • Source: Internet
    • Author: User
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    !---- The definition of background and purpose hematoma enlargement focuses on changes in ventricular volumein-brain hemorrhage (IVH) is a predictor of poor prognosis, but IVH expansion is not included in the current definition of hematoma enlargementstudy aims to assess whether the inclusion of IVH expansion has an impact on the current hematoma expansion assessment of the 90-day prognosismethod uses THE PREDICT-ICH study data to compare the standard hematoma enlargement (-6 mL or 33%) with the improved hematoma enlargement definition (including the presence of IVH or smhthe main result of thewas poor clinical prognosis after 90 days (mRS score was 4-6)calculate diagnostic accuracy for each patient under the definition and compare each definition using C statisticsresults In 127 (49.6%) of the 256 patients who met the inclusion criteria, the mRS score was 4-6The diagnostic sensitivity and specificity of thestandard (n-80) were 45.7% (95% CI, 36.8-54.7), 82.9% (95% CI, 75.3-88.9), and the improved definition of sensitivity and specificity were 63.8% (95% CI, 54.8-72.1), 75.2% (95% CI, CI 82.82), CI 82.82the diagnostic accuracy rate under the definition of improvement, after adjusting the relevant covariates, it was related to a 2.55-fold increase in the adverse prognosis OR value after 90 dayssub-modified definitions (,6 mL or .33% or IVH enlargement s1 mL) have similar sensitivity 56.7% (95% CI, 47.6-65.5), specificity 78.3% (95% CI, 40.2-85.1) and values of 2.40 (95% CI, 1.23-4.69)conclusions in patients with moderate to severe ICH, the inclusion of IVH enlargement in the definition of hematoma enlargement increased sensitivity, and specificity decreased only slightly, increasing the predictive value of the 90-day prognosis
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