Stroke: Effect of sleep breathing on the prognosis of function in patients with ischemic stroke

Cardiopulmonary coupling (CPC) analysis is an easy way to assess sleep apnea (SDB)However, its prognostic effecton on acute ischemic stroke patients needs further studyIn a recent study published in Stroke, an authoritative journal in the field of cardiovascular disease, researchers conducted dynamic electrocardiogram monitoring and CPC analysis of patients in patients in the early stages of non-cardiac embolism ischemic stroke to explore the prognostic effects of SDB on functional impairment in three-month follow-up615 acute non-cardiac ischemic stroke patients from a multicenter, forward-looking population were monitored by dynamic electrocardiogram within 30 days of a stroke attack, CPC analysis, and defined By narrow-band coupling during sleepThe researchers used an improved Rankin scale to investigate the association between SDBs and dysfunction over a three-month period191 (31.1%) of the 615 patients had narrow-band coupling (average age 64.5 to 12.6 years)The narrow-band group developed severe dysfunction during the three-month follow-up (improved Rankin scale score s2; 45.5% vs12.9%, P 0.001) and persistent disability (improved Rankin scale score s.0; 53.9% vs39.8%, P 0.001) has a higher chanceIn multivariate analysis, narrow band coupling is an independent predictor with a higher risk of severe and persistent dysfunction in 3 months (ratio of 3.98 (95% CI is 2.34-;P 6.78) ;P 0.001; The results were consistent after a preference score matching analysis of 157 patients (C statistics s.770)Thus, SDBs assessed by CPC analysis early in ischemic stroke can predict severe and long-term dysfunction at 3 monthsCPC analysis using dynamic electrocardiogram monitoring can help predict functional impairment in patients with acute ischemic stroke