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It is reported that one-third of mild brain stroke early neurological deterioration occurs mainly due to the presence of associated intracranial occlusion
.
Recently, experts from the Department of Neurology in Miami conducted a prospective study to evaluate the vascular occlusion patterns, thrombus characteristics, and recanalization rates of these patients .
It is reported that one-third of mild brain stroke early neurological deterioration occurs mainly due to the presence of associated intracranial occlusion
Among the 575 patients, 12.
9% had an NIHSS score ≤5 (median age, 70.
5[63-79]; 58% were male; NIHSS, 4[2-4])
.
The demographics and vascular risk factors of the two groups were similar
Mild patients have longer time from onset of symptoms to evaluation (from onset to CT examination [240 minutes vs 167 minutes] and CTA [246 minutes vs 172 minutes]), and more distal occlusions (M3, anterior cerebral artery and brain) Posterior artery: 22% vs 6%), higher thrombus burden score (median, 9[6-9] vs 6[4-9]), but similar favorable thrombus permeability (residual flow grade I-II, 21% vs 19%), higher collateral flow (9.
In a model adjusted for gender, alteplase, residual blood flow, and the time between two vascular imaging, intravenous injection of alteplase (OR=3.
Graphical representation of INTERRSeCT experimental research results
It can be seen that compared with moderate/severe strokes, mild strokes with intracranial occlusion have different vascular occlusion patterns, but the thrombus permeability is similar
.
Higher thrombus permeability and the use of alteplase are associated with successful recanalization, although most people do not
It can be seen that compared with moderate/severe strokes, mild strokes with intracranial occlusion have different vascular occlusion patterns, but the thrombus permeability is similar
references:
Radiographic Characteristics of Mild Ischemic Stroke Patients With Visible Intracranial Occlusion: The INTERRSeCT Study.
https://doi.
org/10.
1161/STROKEAHA.
120.
030380 Leave a message here