Stroke: CtP was used to accurately assess the function of acute ischemic stroke side branch circulation.

the !---- background and objectiveS of this study is designed to use CT perfusion imaging to establish and validate the best measurement method for evaluating lateral branch circulation in patients with acute ischemic strokeThemethod in step 1 analysis (n-22), the sacrotum area of ischemic hemispheric side is divided into 6 soft meningi artery regions and the ROC curve analysis to obtain the best side branch threshold, and in step 2 analysis (n-156), the side branch cycle threshold is used to define the side branch cycle indexin Step 2 analysis, the ratio CT perfusion side branch cycle index and dynamic CTA side branch cycle score were used to predict clinical prognosisThe best side-branch cycle threshold forresults was the delay time of 6s (sensitivity and specificity were 88%, 92%, respectively)CT Perfusion Side Branch Cycle Index is defined as delay time of 6s/delay time and 2s volume, showing a significant correlation with the dynamic CTA side branch cycle score (correlation coefficient is 0.62; P.lt;0.001), the optimal truncation for predicted higher side-branch cycling functions was 31.8% (sensitivity and specificity were 83%, 86%, respectively)in the prediction of good clinical prognosis, the delay time lateral branch cycle index shows that it is similar to the predicted value of dynamic CTA (the area under the ROC curve is 0.78 (0.67-0.83) and 0.77 (0.69-0.84), respectively; P.lt;0.001)conclusion CTP can accurately and quantitatively evaluate the lateral branch circulation function of acute ischemic stroke stroke.