Stroke: By the time people reach middle age, what factors affect cognitive function?
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Last Update: 2020-07-16
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Source: Internet
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Author: User
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!---- The relationship between hidden vascular brain injury and cognitive impairment in middle-aged population sourcing and cognitive impairment is not clear at presentstudy to verify that patients with hidden vascular brain injury with cerebrovascular risk indicators have lower cognitive scores? Methods This study included 7547 adult patients withno cardiovascular disease, with an age range of 35-69 years, and detected hidden vascular brain injury (white matter abnormal high signal, cavity cerebral infarction and non-cavity cerebral infarction) by DSS testing and Montreal cognitive evaluation and MRI evaluationuse the INTERHEART risk score to score cardiovascular risk indicatorsuse the multi-mixed model to evaluate the decisive indicator of cognitive function score reductionrisk indicators and signs of MRI vascular brain injury with reduced numeracy scoresthe average age of the subjects was 58 years, with 55 per cent being femaleThe Montreal Cognitive Function Evaluation and SDD Check Scale decreased significantly with age, INTERHEART risk score, and growth, especially in patients with high white matter signal high load, non-cavity cerebral infarction, and 3 plus asymptomatic infarctionadjusted age, gender, education, race, and other covariates, with a significant reduction of 1 point for each 5-point increase in cardiovascular risk score (95% CI, -1.3 to -0.7); 1.9 points lower (95% CI, -3.2 to -0.6) with an increase in the number of abnormally high white matter signals;about 15 percent (95 percent CI, 12-17) of patients with low cognitive function scores, about 19 percent of medium- and high-level cardiovascular risk indicators (95 percent CI, 8-30), and MRI vascular brain injury were about 10 percent (95 percent CI, -3 to 22)Conclusion sandaling This study shows that in middle-aged people, patients with cardiovascular risk factors and MRI vascular brain injury had lower cognitive function screening scoresmainly include low education level, higher vascular risk and MRI vascular brain injury
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