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    Home > Active Ingredient News > Study of Nervous System > Stroke: Blood pressure goals in the first 6 hours after endovascular therapy for stroke

    Stroke: Blood pressure goals in the first 6 hours after endovascular therapy for stroke

    • Last Update: 2022-01-22
    • Source: Internet
    • Author: User
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    Blood pressure typically rises in the first 24 hours after stroke, even after endovascular therapy (EVT), and takes several days to return to baseline levels
    .


    It has been demonstrated that admission blood pressure is strongly associated with functional outcomes after EVT


    In November 2021, Noor Samuels et al.
    from the Netherlands used data from the MR CLEAN Registry to evaluate the association of SBP with functional outcomes and sICH within 6 h after EVT
    .

    We analyzed patient data from eight centers in the MR CLEAN registry for which SBP data were available within 6 h after EVT
    .


    The investigators assessed maximum, minimum and mean systolic blood pressure


    Of the 1796 patients, post-EVT SBP data were available for 1161 patients
    .


    Higher maximal SBP (per 10 mmHg increase) was associated with worse functional outcomes [(adjusted OR, 0.


    The relationship between minimum SBP and functional outcome was non-linear, with an inflection point of 124 mmHg
    .


    SBP below or above the inflection point was associated with poorer functional outcomes [adjusted common OR, 0.


    The authors concluded that maximum SBP within 6 h after EVT was positively associated with worse functional outcomes and increased risk of sICH
    .


    The lower or higher the minimum SBP, the worse the outcome


    Literature source:

    Blood Pressure in the First 6 Hours Following Endovascular Treatment for Ischemic Stroke Is Associated With Outcome.


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