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Stroke: Association between beta-blocker or statin use and risk of cavernous malformation bleeding

 Last Update: 2022-05-23
 Source: Internet
 Author: User

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Cerebral cavernous malformations (CCMs) can manifest as seizures, intracranial hemorrhage, focal neurological deficits, or incidentally on brain magnetic resonance imaging

Seizures, intracranial hemorrhage, and focal neurological deficits can also be detected incidentally on MRI of the brain

A study published in Stroke, an authoritative journal in the field of cardiovascular disease, aims to determine the relationship between beta-blocker or statin use and future symptomatic intracranial hemorrhage or intracranial cavernous malformation (CCM).

The population-based Scottish cohort of adults with intracranial vascular malformations prospectively identified adult residents of Scotland with a first diagnosis of CCM between 1999-2003 or 2006-2010

63 (21%) of 300 adults used beta-blockers (27/63 [43%] propranolol) and 73 (24%) used 3634 visits/years of follow-up statins

CONCLUSIONS: The use of beta-blockers, rather than statins, reduces the risk of intracranial hemorrhage or persistent/progressive focal neurological deficits in patients with CCM

The use of beta-blockers (rather than statins) reduces the risk of intracranial hemorrhage or persistent/progressive focal neurological deficits in patients with CCM

Original source:

Susanna M.

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