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Introduction: since this year, there have been outbreaks of avian influenza in Hunan, Inner Mongolia, Liaoning, Hubei and other places in China In connection with the epidemic situation of avian influenza all over the world and the severe situation of the epidemic situation of avian influenza in China's neighboring countries, we should keep on warning: the prevention of avian influenza should not be relaxed at all Experts cautioned that the occurrence of avian influenza has gone through the process from wild birds to poultry and then to human beings If the boundary of human to human transmission is broken, it will face serious consequences The results show that H5N1 avian influenza virus is very active and mutates rapidly It is possible to break through this boundary In the face of such a situation, on the one hand, we should not take it lightly, on the other hand, we should not panic and treat it rationally with a scientific attitude Any epidemic has obvious epidemic law, so it can be prevented The spread of epidemic must have three links: the source of infection, the route of transmission and the susceptible population These three links must exist at the same time and interact with each other Without any of them, the occurrence of infectious diseases is impossible In the face of the avian influenza epidemic, the party and the government attach great importance to it, and take timely measures such as isolation, slaughter and other measures to control the source of infection and block the transmission path, so that the epidemic can be controlled in a timely and effective manner All over the country have also strengthened preventive measures, invested human and financial resources, increased the management of the market and circulation channels, to ensure the safety of people's lives However, we should also see that the current prevention of avian influenza, China is facing adverse factors Now it is known that migratory birds are the main hosts of avian influenza virus China has a vast area, and almost all of the country is where migratory birds pass by, which makes it more difficult to control the source of infection According to some data, the number of poultry raised in China accounts for a quarter of the world's, and the mode of raising is mainly decentralized People have more opportunities to contact poultry, which greatly increases the probability of human infection with avian influenza Several cases of pneumonia with unknown causes in China have a history of close contact with poultry As for how to prevent avian influenza, scientists pointed out that for a new virus, almost all people do not have immune function and are susceptible to infection At present, it is particularly necessary to prevent the co-existence of human influenza and avian influenza virus in human body, which will provide opportunities for H5N1 mutation and increase the risk of avian influenza outbreak Therefore, for the susceptible population, especially the elderly and children, vaccination is an effective measure At the same time, for most people, developing good habits of living and health can effectively prevent avian influenza In the face of the severe situation of avian influenza, scientists have proposed that scientific means should be adopted to put out the epidemic situation and prevent the avian influenza to the greatest extent in the areas where the epidemic situation has already occurred At present, the international scientific community is strengthening cooperation Scientists are running a race with the variation of avian influenza virus They should take all means to prevent or delay the spread of avian influenza to people The cooperation of the public will win time for scientific research, so that human beings can gather wisdom and strength, and finally win the battle