Stem cell therapy may be used to treat children's neuroblastoma
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Last Update: 2018-09-03
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Source: Internet
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Author: User
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Recently, a series of breakthroughs may provide more effective methods for the treatment of common brain cancer in children Scientists from the University of North Carolina, Lineberger comprehensive cancer center and UNC eshelman School of Medicine reported the results of early studies that showed that stem cells induced from skin cells could track and release drug (http://www.chemdrug.com/) to destroy hidden neuroblastoma cells after surgery Previously, preclinical studies by Dr Shawn hingtgen and others from UNC showed that they can transform skin cells into stem cells, which can release drugs to kill glioblastoma In their new study, published in the journal PLoS One, the method has been shown to have a significant effect on killing neuroblastoma and prolonging its life span The study is a necessary step in the development of clinical trials (http://www.chemdrug.com/sell/24/) and will determine whether the method is suitable for the treatment of childhood related cancer In this study, researchers reprogrammed skin cells into stem cells and then genetically engineered them When the modified cells are exposed to another drug called prodrug, they will be toxic to other cells The experimental results showed that the implantation of stem cells with drugs into the brain after operation could reduce the tumor size by 15 times and prolong the median survival time of mice by 133%.
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