State Food and Drug Administration: adverse drug reactions in elderly patients increased by 2.1%

Source: on July 17, 2015, the State Food and Drug Administration issued the national ADR monitoring annual report (2014) The report shows that the coverage of ADR reports in China has been broadened, the ability of finding and collecting ADR information has been enhanced, and the public awareness of drug safety has been further improved According to statistical analysis, the number of reported anti infective drugs still ranks first, and medical institutions are still the main source of adverse reactions, accounting for 82.2% of the reported number In terms of drug varieties involved, the number of reported anti infective drugs still ranks first among all kinds of drugs, but the reported proportion has been declining for five consecutive years; the number of reported cardiovascular system drugs is 135000, up 0.2 percentage points from 2013 In terms of drug dosage forms, the proportion of injection reports is still high, accounting for 60.9%, 2.2 percentage points higher than that in 2013, and the proportion of oral preparations accounts for 35.2% Among the adverse drug reactions / events reported in 2014, the top three involved systems were skin and its accessories damage (27.8%), gastrointestinal system damage (26.3%) and systemic damage (12.2%), and the sum of the top three was 66.3% The average number of case reports per million population is one of the important indicators to measure the level of ADR monitoring in a country The State Food and Drug Administration pointed out that with the joint efforts and participation of drug regulatory departments at all levels, health administrative departments, ADR monitoring institutions and medical institutions, the level of ADR monitoring in China was further improved in 2014, and the number of reports was close to the level of developed countries In counties, the coverage rate of ADR reports reached 94.4%, and the average number of ADR reports per million population in China reached 991, an increase of 0.8 percentage points compared with 2013 According to the statistics of the age of patients involved in the report, 10.5% of the public reported adverse drug reactions, which was basically the same as that in 2013 19.9% of the public reported adverse drug reactions, which was 2.1 percentage points higher than that in 2013 According to the analysis of the national ADR monitoring database, since 2009, the proportion has continued to rise In serious ADR reports, the proportion is higher, accounting for 27.3% The State Food and drug administration suggested that: first, pay attention to the safety of anti infective drugs for children, use anti infective drugs strictly according to the instructions, especially for young children, use anti infective drugs carefully and reasonably; second, pay attention to the combined use of drugs for elderly patients, and suggest that the elderly patients should take individual drugs as much as possible, reduce the types of drugs used together, and pay attention to the way and time of administration; 3、 We should pay attention to the safety of traditional Chinese medicine injection in primary medical institutions, and strengthen the propaganda of rational drug use and the training of emergency treatment The State Administration of food and drug reminded that adverse reactions occurred in the course of drug use should be reported to the doctor in time, or to the drug production and trading enterprises or local drug adverse reaction monitoring agencies.