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    Home > Active Ingredient News > Immunology News > Sjogren's syndrome is quick solution

    Sjogren's syndrome is quick solution

    • Last Update: 2022-11-14
    • Source: Internet
    • Author: User
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    What is Sjogren's syndrome?

    Sjogren's syndrome is a systemic autoimmune disease characterized by the involvement of exocrine glands such as salivary glands and tear glands, these glands can not normally secrete saliva, tears, etc.
    , so it is mainly manifested as dry mouth, dry eyes, severe cases need to be taken with water for dry food, and even want to cry without tears and so on
    .

    Sjogren's syndrome can be divided into primary Sjogren's syndrome and secondary Sjogren's syndrome, which is secondary to other autoimmune diseases such as rheumatoid arthritis and systemic lupus erythematosus
    .

    Sjogren's syndrome requires early recognition and treatment 

    The disease not only invades the exocrine glands, but also invades multiple organs and systems throughout the body, such as respiratory, digestive, nervous system, etc.
    , resulting in a variety of complex clinical manifestations
    .
     

    However, patients do not know that these symptoms are caused by a disease, nor do they know that it belongs to rheumatology and go to the rheumatology department, often to stomatology, ophthalmology, orthopedics, respiratory and other departments, and most patients develop symptoms slowly, a considerable number of patients from the beginning of symptoms to diagnosis takes 5~10 years, so often delay diagnosis for many years, So that patients cannot receive timely treatment
    .
     

    The manifestations of Sjogren's syndrome are varied

    Dry nose and mouth, difficulty swallowing foods such as steamed buns, dry, ulcerated or mirror-like
    tongue surface.

    Fewer dry eyes, a foreign body sensation, repeated purulent infections of the cornea or conjunctiva, and even decreased
    vision.

    Multiple uncontrollable caries, darkening of teeth, loss of small pieces
    .

    The parotid and submandibular glands are repeatedly enlarged and painful
    .

    Generalized fatigue, low-grade fever, muscular arthralgia, muscle weakness
    .

    Vaginal, dry skin, pruritus, purpuric rash
    .

    If there are the above symptoms, combined with blood sampling and B-ultrasound and other related examinations, it can be determined whether you have Sjogren's syndrome
    .
    So what do people with Sjogren's syndrome need to pay attention to in their daily lives?
      

    Oral care and treatment of xerostomia

    For patients with xerostomia, smoking and drinking should be avoided, and drugs that cause aggravation of dry mouth such as atropine, phenothiazines, tricyclic antidepressants, antispasmodics, antiparkinsonians, and long-term use of H2 blockers including cimetidine, ranitidine and famotidine
    .

    Pay attention to oral hygiene, do a good job of oral care, be sure to use a toothpick to remove food debris after meals, and rinse your mouth frequently to reduce dental caries and secondary oral infections
    .

    When mouth sores occur, care should be taken to clean the mouth to avoid infection
    .
     

    Eye care and treatment of dry eyes 

    Preparations that reduce tear secretion, such as diuretics, antihypertensives, and antidepressants
    , should be avoided as much as possible.

    The use of artificial tears (sodium hyaluronate) to point the eyes and improve the environment (such as the use of humidifiers) can relieve dry eyes, and the use of chlortetracycline eye ointment and moisturizing eye drops can protect the cornea, reduce corneal damage and discomfort, and reduce the chance of
    infection.
    If corneal ulceration develops
    , aggressive ophthalmologic treatment
    is recommended.
     

    Skin care

    For dry skin, desquamation and itching caused by sweat gland involvement, use less or no alkaline soap, and choose neutral soap
    .
    Compound glycerin anti-itch milk, vitamin
    E milk and commercial body lotion can be used to protect the skin very well
    .
    Change your clothes and bedding frequently to keep your skin clean
    .

    Patients with skin lesions in primary Sjogren's syndrome should be debrided and replaced according to the skin lesions, and antibiotics
    can be used appropriately in case of infection.

    There is vaginal dryness, itching, burning pain during sexual intercourse, should pay attention to genital hygiene, can appropriately use Jieer Yin lotion or lubricants such as glycerin, castor oil, etc.

    Respiratory care

    Controlling indoor humidity at 50%~60% and maintaining a temperature of 18~21 °C can relieve symptoms such as dry cough caused by dry respiratory mucosa and prevent infection
    .

    Patients with thick sputum that is difficult to cough up can be aerosolized inhalation
    .
    Antibiotics and chymotrypses may be added if necessary to control infection and promote expectoration
    .

     

    References:

    [1] Zhang Wen, Li Xiaomei, Xu Dong, etc Diagnosis and treatment of primary Sjogren's syndrome[J].
    Chinese Journal of Internal Medicine, 2020, 59(4): 269-276

    [2] Rheumatology Branch of Chinese Medical Association Diagnosis and treatment of Sjogren's syndrome[J].
    Chinese Journal of Rheumatology, 2010, 11(14).

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