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Significantly prolong the life combination therapy of specific prostate cancer patients to reach the primary clinical endpoint of phase 3

 Last Update: 2022-01-11
 Source: Internet
 Author: User

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On December 3, 2021, Bayer and Orion announced that a phase 3 clinical trial of the oral androgen receptor inhibitor (ARi) Nubeqa (darolutamide) has reached the primary endpoint

Prostate cancer is the second most common cancer in men in the world and the fifth leading cause of cancer deaths in men

Nubeqa has a unique chemical structure, can bind to androgen receptor with high affinity and exhibits strong antagonistic activity, inhibiting the transfer of androgen receptor to the nucleus and its mediated gene expression, thereby inhibiting the proliferation of prostate cancer cells Purpose

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Reference materials:

[1] Phase III Investigational Trial of Nubeqa® (darolutamide) in Combination with Docetaxel and Androgen Deprivation Therapy (ADT) Meets Primary Endpoint of Significantly Increasing Overall Survival (OS) in Patients with mHSPC.

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