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Immunotherapy is a hot topic
The efficiency of antigen cross-presentation depends primarily on intracellular antigen stability and retention time
Based on the above, based on the gelation reaction between graphene oxide (GO) and metformin hydrochloride, Shen Qi's research group loaded the metabolic nanointervening agent (Man-OVA(RSV) NPs) of DCs into a multifunctional hydrogel system (Gel@NPs
The work is titled Reprogramming dysfunctional dendritic cells by a versatile metabolism nano-intervenor for enhancing cancer combinatorial immunotherapy, recently published in the internationally renowned academic journal Nano Today, The first author of the paper is Yang Jie
Shen Qi's research group
Faculty of Pharmacy