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    Home > Biochemistry News > Biotechnology News > Shanghai Jiaotong University issued a document: Childhood exposure to triclosan may affect the physical development of 7-year-old children

    Shanghai Jiaotong University issued a document: Childhood exposure to triclosan may affect the physical development of 7-year-old children

    • Last Update: 2022-10-02
    • Source: Internet
    • Author: User
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    Tian Ying and Gao Yu's research group in the School of Public Health of the Faculty of Medicine published a paper entitled "Associations between repeated measurements of childhood triclosan exposure and physical growth at 7 years" in Chemosphere No.


    triclosan (TCS) is a broad-spectrum antimicrobial agent that is widely used in a variety of household and personal care products such as toys, kitchenware, cosmetics, lotions, shampoos, cleansers, shower gels, soaps, toothpastes and mouthwashes


    In vitro and in vitro experimental studies have shown that TCS exposure may affect the growth and development of offspring due to the endocrine interference properties of TCS


    This study was based on children in the Laizhou Wan Birth Cohort (LWBC) established in the Laizhou Bay area of Shandong Province, with a total of 206 children


    The results showed that the concentration of creatinine after correction in urine showed a downward trend at the follow-up of children at 1, 2, 5 and 7 years of age, with the potential levels of 0.


    Children's urine TCS levels tend to change with age

    The study also found a positive correlation between TCS exposure and waist-high ratio at age 7 years (β = 0.


    Repeated measurement of the relationship between TCS exposure and physical development at age 7 years of age in childhood (n = 206)


    After sex stratification, the relationship between TCS exposure and physical development at age 7 years was repeatedly measured in childhood

    Previous studies have focused on the effects of single-point TCS exposure, and few studies have explored


    Chen Minyan, a 2020 master's student at the School of Public Health of Shanghai Jiao Tong University School of Medicine, and Hu Yi, International Peace Maternal and Child Health Care Hospital affiliated to Shanghai Jiao Tong University School of Medicine, are the co-first authors of the paper, and Professor Gao Yu and Professor Tian Ying of the School of Public Health of Shanghai Jiao Tong University School of Medicine are the co-corresponding authors


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