Semin Arthritis Rheu: Characteristics and outcomes of patients with diseased macroblastitis in the eye

The study was designed to describe the characteristics and prognosis of patients with clottel arteritis (GCA)-related eye injuries at the time of diagnosisa retrospective single-center cohort study of 409 continuing GCA patients, 104 of which had visual symptoms at GCA diagnosis, and the researchers compared them to 104 age and gender-matching eye-free controlsEach visual symptom is associated with an ophthalmic diagnosis, which is re-evaluated by an ophthalmologistcompared to the control group, patients with visual symptoms had less fever (p-0.0006) and rheumatic polymyalgia (p-0.02) and lower levels of acute stage reactants (p-0.004)Prior to GCA diagnosis, patients described four visual symptoms: blurred vision (60 per cent of the patient), a sexual black hichea (18 per cent), multiple vision (13 per cent) and permanent vision loss (9 per cent)In 47 patients (45%), there was a pre-ischemic optic neuropathy (AION), followed by 15 patients (15%) with central retinal artery obstruction (CRAO)In 2 patients, both conditions existed at the same timeThere was no difference in delayed treatment of glucocorticoids in patients with or without visual symptoms (p-0.06)In 60 patients with initial AION and/or CRAO, 39 (65%) sustained blindness or severe vision impairment, although 45 (75%) received metastasis with methicillin vein (IV) shock therapyDespite the onset of treatment, 4% of patients with visual symptoms develop new ischemic events (all AION)the study observed that a quarter of GCA patients had eye damageAION is still associated with the worst vision prognosis, and IV-meth nylon shock therapy does not reduce the risk of blindness