Semin Arthritis Rheu: Cervical artery plaques can predict cardiovascular events in patients with rheumatoid arthritis
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Last Update: 2020-05-29
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Source: Internet
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Author: User
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The study aims to explore whether a forward-looking definition of population-based rheumatoid arthritis (RA) initial queue, systemic coronary risk assessment (SCORE) and QRISK3 algorithms, and cervical arterial ultrasound can predict cardiovascular (CV) events and deaths327 patients with no history of diabetes, chronic kidney disease or CV events were studied between 2012 and 2013 by cervical arterial ultrasoundAt that time, CV risk was calculated based on the improved EULAR RA Systemic Coronary Heart Risk Assessment (mSCORE)A five-year prospective follow-up study was conducted through the survival analysis modelThe EULAR mSCORE and QRISK3 algorithms based on the 2015/2016 updated EULAR guidelines were reviewed using baseline dataAfterfollow-up of 1,984.25 patients, 23 patients died and 27 CV events occurredThe linear mortality rate was 1.16/100 years (95% confidence interval: 0.74-1.73)After adjusting the age, sex and course of disease, the model of the cervical artery plaque (risk ratio of 6.10 (HR): 6.10(95% CI: 0.74-50.0 ;p) and another model using cervical artery plaque and QRISK3 (cervical artery plaque: 6.12 (95%CI:0.74-50) ;p s 0.09 and QRISK3 per 1% HR: 1.03 (95% CI: 0.99-1.07) p.11) are the best predictors of death, while the model using the cervical artery plaque (HR:5.25 s/95%CIS: 1.41-19.50) is the best predictor of death; p-0.01) and another model using cervical artery plaques and QRISK3 (cervical artery plaque HR: 5.13 (95% CI: 1.36-19.3); The HR of p.02 and QRISK3 per 1% is the best predictor of CV eventsIn contrast, mSCORE is a weaker predictor of death or CV event riskthe presence of cervical artery plaques incan predict CV events and deaths in RA patientsIn RA patients, the predictive ability of cervical artery plaques and QRISK3 was higher than mSCORE
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