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| Scientists reach a new international consensus on the concept of epigenetics |
Recently, " Nature Reviews Gastroenterology & Hepatology " ( Nature Reviews Gastroenterology & Hepatology ) published a new international consensus on the concept of epigenetics
.
With the deepening of research on the frontier scientific issues of intestinal flora, probiotics have received extensive attention as an important industry and application export
.
In addition to traditional probiotics, more and more new genera and species have been reported recently, and they are expected to become new types of probiotics, demonstrating broad development prospects in this field
In 2019, the International Association of Probiotics and Prebiotics (ISAPP) published a consensus on the concept of epigenes in Nature Reviews Gastroenterology & Hepatology , defining epigenes as “to host Inactivated bacteria and/or bacterial components that play a beneficial role"
.
In this definition, inactivated probiotics are also classified as epibiotics
Nature Reviews Gastroenterology & Hepatology
The publication of this definition has aroused extensive discussion in the international academic community
.
Recently, Professor Maria Rescigno, the vice president of the Italian University of Humanities, initiated 38 scientists from 33 units around the world to participate in a discussion and motion on the definition
This consensus believes that the epibiotics should only include molecules or molecular combinations derived from probiotics that are beneficial to the host and have clear ingredients.
Inactivated bacteria should not be included in the category of epigenes
.
Because the beneficial functions of inactivated bacteria may be a variety of unknown and complex components, and factors such as synergistic effects are involved, there is no essential difference from probiotics in that the functional components are not clear
This statement has important guiding value for the normative development of R&D in the field of epigenetics
.
(Source: China Science News Li Chen Gaoge)
Related paper information: https://doi.
https://doi.
org/10.
1038/s41575-021-00522-5
