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Scientists map skin cells that cause diabetic foot ulcers

 Last Update: 2022-01-25
 Source: Internet
 Author: User

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Diabetic foot ulcers—open sores or wounds that don’t heal—are a devastating complication that affects more than 15 percent of people with diabetes and accounts for more than 70,000 lower-extremity amputations each year in the U.

To better understand what causes diabetic foot ulcers and how to treat them, researchers at Beth Israel Women's Pastoral Medical Center (BIDMC) and Emory School of Medicine compared cells from patients with ulcers that healed with those from patients whose ulcers did not heal, and Cells extracted from intact forearm skin of diabetic and non-diabetic patients

"Various types of cells, including endothelial cells, fibroblasts, keratinocytes, and immune cells, play important roles in the wound healing process, but little is known about their role in impaired wound healing in diabetic foot ulcers

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