Scientists have proposed a framework for precise study of nutrition science

"Everyone wants a "one size fits all" diet when intervening, and in our laboratory and some other work has shown that this just won't be the case," said Kapahi, whose team is committed to understanding the mechanisms of nutrition signals and metabolism that affect aging and Aging-related diseases

Studies on genetically different strains of fruit flies show that precise nutrition is required

In 2020, Buck postdoctoral fellow Dr.

“I think it’s important for everyone in the field to understand and recognize that there are many different ways to look at what an intervention might do

What is included in the review

This review details several forms of dietary restriction (from calorie restriction to various forms of intermittent fasting, and diets that restrict protein, carbohydrates, specific amino acids, micronutrients, and metabolites), and details yeast, Related effects of worms, flies and mice

The author introduces the complexity of measuring the effects of dietary restriction on aging, explains how lifespan analysis can explain the mechanisms of dietary restriction, the possible lifespan response of specific genes to dietary interventions, and the role of gender in male and female species

Kapahi said: "We want to give scientists who are entering the field of aging research an overview so they can start to distinguish between forests and trees in terms of dietary restrictions

For better or for worse-our understanding of humans and dietary restrictions

The review also includes reported data on the effects of restricted diets on humans

The researchers said that in terms of normal aging, dietary restrictions may have broad benefits for many physiological systems, but data shows that restrictive diets have a negative impact on wound healing and may affect our ability to recover from fractures

"The age of people using dietary restrictions is also a factor that needs to be studied and considered," Wilson said

What about gender?

Capali said that gender is one of the main factors that cause people to respond differently to dietary restrictions.

Women are at greater risk of Alzheimer's disease

Impact on clinical trials and potential interventions

Kapahi said that adopting an individualized approach to dietary restriction can lead to more targeted and informative clinical trials because researchers can identify and recruit people who are more likely to respond to specific interventions

Journal Reference :

1. Kenneth A.