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Cells with mutations in the EGFR and KRAS genes become cancerous when exposed to air pollutants
The latest data paves the way for new approaches to lung cancer prevention and treatment
According to the latest data, a new mechanism has identified that very small particles of pollutants in the air can lead to lung cancer in people who have never smoked, paving the way
"Particles from fossil fuel combustion in the air exacerbate climate change, directly impacting human health
The new findings are based on human and laboratory studies of a genetic mutation called EGFR, which occurs
In laboratory studies, scientists at the Francis Crick Institute showed that the same pollutant particles (PM2.
In the final series of experiments, Francis Crick's team used a state-of-the-art, ultra-deep mutation analysis of small samples of normal lung tissue, and found EGFR and KRAS driver gene mutations in 18 percent and 33 percent of normal lung samples
"We found that the driver mutations in the EGFR and KRAS genes, which are common in lung cancer, are actually present in normal lung tissue, which may be the result of
Tony Mok of the University of Chinese in Hong Kong, who was not involved in the study, said: "This study is interesting and exciting because it means that we can ask whether in the future, it is possible to use lung scans to look for precancerous lesions in the lungs and try to reverse them
Like Swanton, he stressed the importance
