Scientists have been studying the first scorpion gene map for 20 years. Peptide drugs have gained a lot
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Last Update: 2013-11-04
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Source: Internet
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Author: User
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Scorpions have a history of 400 million years Scientists in Wuhan and Shanghai now unveil them Study for 20 years and draw the first scorpion genome map It provides a reliable basis for finding new drug precursors (Wuhan Evening News reporter Qu Jiancheng, correspondent Yang Xinxin) scorpion has a strong ability to survive So, how do scorpions, with a history of 400 million years, adapt to extreme environment? After 20 years of research, experts from Wuhan University and Shanghai Biological Information Technology Research Center have drawn the genome map of scorpions for the first time in the world, revealing that Scorpions, a unique arthropod adaptation model, have been adapted to the environment Recently, their research results were published in the journal Nature commun Li Wenxin, Professor of Wuhan University, Li Yixue, researcher of Shanghai Institute of life sciences, Chinese Academy of Sciences, and Li Xuan are co authors of this paper After 400 million years of survival and evolution, scorpion still retains the main morphological and structural characteristics of ancient ancestors, so it is regarded as "living fossil" Scorpion can adapt to all kinds of extreme environment very well, and has a strong survival ability Except for the Antarctic, all continents can find the footprints of scorpion Researchers from Wuhan University have been systematically studying scorpion and its toxins for nearly 20 years, and have made a series of achievements in the research of scorpion resources and scorpion toxins in China In the world, it is the first to complete the genome sequencing of Martha martensii, the largest scorpion species in the world, and predict 32016 protein coding genes Martha martensii has been used in the treatment of rheumatoid arthritis, stroke, epilepsy and chronic pain for more than 2000 years Many active ingredients in scorpion venom have become important resources for the development of modern biological drugs, such as neurotoxin, antitumor peptide, antiviral and superbacterial peptide The analysis of the genome of Martha martensii reveals the diversity of scorpion toxins, which provides a reliable basis for searching for new functional molecules and even drug precursors.
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