Scientists from Jilin University extracted effective components of anti gout from sunflower flower disk

July 4, the reporter recently learned from Jilin University that Liu Xiaobo, a professor in the school of life sciences of Jilin University, extracted the effective anti gout ingredients from sunflower flower plate This achievement has been published in "medicine and health" and other domestic professional medical journals, and obtained two national invention patents Gout is due to the disorder of purine metabolism in human body, the increase or decrease of uric acid synthesis, resulting in hyperuricemia In severe cases, joint disability and renal insufficiency may occur Gout and diabetes are also called "immortal cancer" in the medical field According to some data, the number of hyperuricemia patients in China has reached 170 million, and the number of gout patients has exceeded 80 million, with a rapid growth rate of 9.7% every year There is no effective treatment and method for gout at present Most of the commonly used special drugs at home and abroad are to inhibit purine metabolism so as to reduce uric acid However, this kind of treatment is helpless for the acid urine salt crystal (gouty stone) The more and more the uric acid salt crystal of patients accumulates in the body, causing joint swelling and pain, and seriously endangering human health Moreover, most of the existing drugs for gout can not overcome the side effects of the drugs themselves on the liver and kidney damage of the drug users "To solve gout, we need to break through three problems: reducing uric acid quickly and safely, dissolving gout stone, not damaging liver and kidney." Professor Liu Xiaobo said After five years of research and development, Liu Xiaobo's team extracted bioactive ingredients such as alkaloids, flavonoids, protein small molecule peptides from sunflower flower flower plates planted in saline alkali land Pharmacological and pharmacodynamic analysis showed that alkaloids have the therapeutic effect on gout They can specifically combine with uric acid to form sunflower alkali uric acid complex, which is excreted by kidney after metabolism by liver As an enzyme preparation that can be directly absorbed by intestine, small molecular peptide can enter into the blood to regulate the metabolism of uric acid and renal tubular transporter, control the generation of uric acid, increase the excretion of uric acid and dissolve it Flavonoids can inhibit the chemotaxis of inflammatory cells and reduce the release of inflammatory factors, which has a unique anti-inflammatory, detumescence and analgesic effect on acute gouty arthritis.