Scientists found that the cancer released killer peptide, which could "wipe out all the drug-resistant cancer cells together"

Is chemotherapy effective or ineffective? It should be said that it is effective for some cases and can even be cured, but it is ineffective for others If it is abused improperly, it may also have adverse effects Not only chemotherapy, but also surgery and radiotherapy It is often seen that some patients with the same cancer have been cured after chemotherapy, while others have not been treated with the same drugs Even for the same patient, the effect of the first chemotherapy is very good When the same chemotherapy scheme is used for treatment, the effect will be reduced or not at all It is difficult to achieve the effect of the first treatment by using other drugs This is because cancer cells have drug resistance to drugs After chemotherapy, the toxicity of cancer cells increased greatly In a new study at the University of Kentucky, researchers at the cancer center show that after cancer cells that are sensitive to treatment die, they release a "killer peptide" that can wipe out cancer cells that are resistant to treatment Recurrence after cancer treatment is a common problem and the biggest cause of cancer death This is because primary tumor cells usually contain cancer cells resistant to treatment These cancer cells continue to spread, leading to the final recurrence of cancer In the new study, published in cancer research, scientists found that cancer cells sensitive to therapy release a peptide called PAF PAF can destroy cancer cells resistant to treatment and effectively inhibit the growth of metastatic tumors In addition, PAF can only enter into cancer cells and has no effect on healthy cells The results show that this naturally occurring substance can be used to target adjacent or distant cancer cells to solve the problems of tumor metastasis and treatment resistance Researchers from the University of Kentucky and the University of England School of medicine pointed out in the report: "in experiments on mice, we found that PAF can successfully enter into the cancer cells, killing all the cancer cells resistant to treatment without damaging the healthy cells of mice The new research is crucial for doctors to plan their treatment and use peptides released by cancer cells that are sensitive to therapy to help eliminate resistant cells At present, we are developing methods that can be used to block resistance and treat cancer cell metastasis "