Scientists analyze COVID-19 protein in attempt to crack gene protection

2020 May 14 News /BioValleyBIOON / - A team of researchers at York University have created a protein, this protein can be stored and protection SARS-CoV-2 virus genome, and SARS-CoV-2 virus can cause COVID-19, this protein as a possible antiviral therapy paved the wayResearchers fromstructure York Biology Laboratory (YSBL) has been purified nucleocapsid protein of the virus, and begins its characterizationThis is the most abundant viral protein, to protect itsgenetic material --RNAThe team is working with cryo-electron microscopy lab at the University of Leeds, trying to determine the precise three-dimensional structure of a protein, to provide information for the mechanistic understanding and drug developmentSource: https: //cn.bing.comantibody testas an important byproduct of this protein provides scientists from other laboratories Sheffield, Oxford and London and they used to make the system of this protein to help develop antibody test for COVID-19'snucleocapsid protein of a strong antibody response in infected individuals, is an important part of the detection processlink between the viral genome and the nucleocapsid protein is an important stage in the viral life cycle can be used as a target of antiviral drugsexclusive use of cryo-electron microscopy and x-ray crystallography of viral proteins and whole virus particles imaged by the Wellcom Foundation senior fellow at the research team led by Professor FredAntson to understand how they are assembledWith the scale of the threat of emerging coronavirus causes becomes apparent, the team quickly focused on the study of SARS-CoV-2The study three-dimensional image participation of doctoral DorothyHawkins explained that the production of three-dimensional image of this protein is essential for understanding the virus "because it is a new virus, any protein it we have no specific information We tried to get genetic material and protect its three-dimensional structure of the protein If we to get a detailed 3-dimensional structure, which will be able to design drugs to prevent contact between them to provide information "
Dorothy added:." scientific community really come together the more we understand, we will the more likely destroy the virus each person in different laboratories are eager to work, all of the competition have been abandoned I think the progress is very fast, because everyone is sharing something as quickly as possible this is a very exciting project "
(bio Valley Bioon.com) references: ScientistsanalyzeCOVID-19proteininabidtocrackgeneticsafeguard