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Oct 17, 2020 /--- -- The new coronavirus SARS-CoV-2, which causes coronavirus disease (COVID-19) in 2019, is now raging around the world.
in a new study, researchers from research institutions such as the University of Toronto and the Lunefeld-Tarenbaum Institute used saliva and blood samples from PATIENTS to measure and compare antibody levels more than three months after symptoms.
found that antibodies against the virus can last at least three months after a person is infected with SARS-CoV-2.
study was published in the October 8, 2020 issue of the journal Science Immunology under the title "Persistence of serum and saliva antibody responses to SARS-CoV-2 Spike antigens in COVID-19 patients."
images from Science Immunology, 2020, doi:10.1126/sciimmunol.abe5511.
the researchers found that IgG antibodies combined with SARS-CoV-2 prickly proteins (S proteins) could be detected for at least 115 days, the longest interval ever measured.
study also showed for the first time that these antibodies can also be detected in saliva.
, co-author of the paper and professor of immunology at the University of Toronto, said, "Our study shows that IgG antibodies against this viral tingling protein are more persistent in both blood and saliva."
our study suggests that saliva may be an alternative to antibody testing.
saliva is not as sensitive as serum, it is easy to collect.
saliva test was developed at the University of Toronto, and a team led by co-author Anne-Claude Gingras, a professor of molecular genetics at the University of Toronto, conducted serum testing.
, "This method of detecting antibodies in the serum or blood is very powerful and is ideal for assessing the prevalence of infection in the community," said Gingras.
this is another tool that can help us better understand or even overcome the virus.
"Most people recovering from COVID-19 have antibodies specific to the virus in their blood."
these antibodies can be used to indicate who has been infected, regardless of whether they have symptoms.
the persistence of antibody responses to SARS-CoV-2 has been debated in recent months.
, published earlier this week in the journal Nature Medicine, showed that for some people infected with the virus but did not show symptoms, antibodies can disappear after two months.
While the researchers acknowledge that they still don't know much about the antibody response to SARS-CoV-2 infections, including how long antibodies last after this period, or how protective they are against re-infection, the study could have broader implications for developing effective vaccines.
, "This study shows that if the vaccine is well designed, it has the potential to induce a lasting antibody response that helps protect inoculators from SARS-CoV-2 infection."
" (bioon.com) Reference: 1.Kento T. Abe et al. Persistence of serum and saliva antibody responses to SARS-CoV-2 spike antigens in COVID-19 patients. Science Immunology, 2020, doi:10.1126/sciimmunol.abe5511.2.Coronavirus antibodies last at least three months after application, U of T finds