Science: New study gives hope to people with diabetic retinal lesions.

21, 2020 /---Xin--- -- According to a new study published recently in the journal Science, the authors reveal the underlying mechanisms of retinal lesions in patients with diabetic retinal lesions.
findings may help develop treatments for these serious diabetes complications.
study was carried out by Dr Jean-Sébastien Joyal and others from the CHU Saint-Justine Research Centre affiliated with the University of Montreal.
(pictured) Diabetic retinal disease is characterized by vasody, which then forms abnormal blood vessels in the retina.
this vasody can damage nerve cells that transmit information from the eyes to the brain.
the study, blood vessels used a series of molecular "brakes" to stop abnormal vascular growth, which were activated in an accelerated manner similar to natural cell aging.
, these mechanisms are clearly activated in a process called cell aging, which eventually leads to scarring of retinal tissue.
when in aging mode, the inflammatory molecules produced by blood vessels become targets for immune cells called neutral granulocytes.
is thought to be the first reaction of the immune system, studies have shown that neophils lag relatively late in reaching the retina, mainly to help clean and reshape damaged blood vessels.
more broadly, the results of this study suggest that the destruction of aging blood vessels leads to beneficial vascular remodeling processes.
, the study provides an understanding of endothoste cell function and reveals the causes of complications such as myocardial infarction, atherosclerosis and stroke in older populations.
(bioon.com) Source: Forward discovery for patients with diabetic retinopathy Original source: Neutrophil extracellular traps target senescent vasculature for tissue remodeling in retinopathy, Science (2020). science.sciencemag.org/cgi/doi ... 1126/science.aay5356.