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Science Immunology: Defects in macrophage development lead to lung disease

 Last Update: 2022-10-02
 Source: Internet
 Author: User

Macrophages lack the necessary cellular tools

Disorders of gene regulation lead to defects

"This regulatory gene is the transcription factor C/EBPb

The significance of this new discovery is not limited to PAP disease

"Maybe we can draw on alveolar macrophages in the lungs and translate our findings into other macrophages that help them digest lipids more efficiently

essay

C/EBPβ regulates lipid metabolism and Pparg isoform 2 expression in alveolar macrophages

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