Science heavy cover: Chinese team released the world's first brain regeneration map!

Xinzhiyuan report

[New Wisdom Introduction] If the brain is 100% developed, will the "super body" become a reality? Recently, Chinese scientists created the world's first spatial-temporal map of salamander brain regeneration, and the research results appeared on the cover of Science

Remember, the human brain has 86 billion neurons that are connected to each other
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Dr.
Yin Gu, the co-corresponding author of the paper and deputy director of BGI-Research, said,

Using the salamander as a model organism, we have identified key cell types during brain regeneration
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This discovery will provide new ideas and guidance for regenerative medicine of the mammalian nervous system
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Therefore, a major goal of CNS regenerative medicine is to reconstruct not only the spatial structure of neurons, but also the specific patterns of their intra-tissue connections
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In future studies, it will be important to reconstruct the 3D structure of the brain and understand the systemic responses of brain regions during regeneration
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Scientists have long dreamed of understanding how the nervous system works by mapping the structure of the entire brain's neural network
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For example, in 2019, Google first reconstructed a 3D model of the neurons of the Drosophila brain, followed by the release of the Drosophila “hemibrain” connectome the following year
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Today, they have released a dataset on human brain imaging
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Through this data set, people can see 130 million synapses, samples of tens of thousands of neurons, which can help people understand the 3D structure of the brain
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In addition to salamanders, scientists have used spatiotemporal omics technology to map the embryonic development or organs of four model organisms, mouse, zebrafish, Drosophila, and Arabidopsis for the first time
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At present, the research results have been published in Cell and its sub-journal Developmental Cell
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Netizens are optimistic about the future development of this research on brain regeneration
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