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September 14, 2020 // -- Pancreatic cancer is rarely detected at an early stage, as symptoms usually do not show until the cancer progresses, and the usual treatments for pancreatic cancer include surgery, chemotherapy, or radiotherapy.
'If we diagnose pancreatic cancer as early as possible, clinicians will treat patients in a timely manner, ultimately helping to improve their treatment and prognosis, and by taking blood samples from patients in a minimally invasive way, researchers will be able to analyze exosomes present in the blood that contain biological information from normal and tumor cells,' said Professor Sentil Kumar, a researcher at medicalxpress.com.
The researchers then analyzed blood samples from patients with pancreatic cancer at different stages and healthy individuals to identify a new type of RNAs that could be used to effectively distinguish between pancreatic health and cancerous conditions;
the researchers point out that identifying these specific biomarkers may help us analyze an individual's susceptibleness to pancreatic cancer, and our ultimate goal is to give patients a good understanding of their condition so that timely measures can be taken to effectively prevent the occurrence of pancreatic cancer.
are still in the early stages of these studies, and later researchers need to study more patients, hoping to identify more specific biomarkers for early diagnosis of pancreatic cancer.
researchers say identifying specific biomarkers in different populations may ultimately help develop more personalized cancer treatment plans and improve patient prognostication.
() Original source: Kumar, S.R., Kimchi, E.T., Manjunath, Y. et al. RNA cargoes in extracellular vesicles derived from blood serum in pancreas associated conditions. Sci Rep 10, 2800 (2020). doi:10.1038/s41598-020-59523-0.