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    Home > Active Ingredient News > Antitumor Therapy > Sci Rep: Road transport workers are at higher risk of cancer

    Sci Rep: Road transport workers are at higher risk of cancer

    • Last Update: 2021-01-15
    • Source: Internet
    • Author: User
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    It is well known that occupational diseases are closely related to cancer.
    workers in coal mines, petroleum, chemicals and steel are at higher risk of lung cancer, and for drivers, long-term exposure to vehicle engine exhaust can cause metabolic system disorders and even multiple cancers.
    Automotive engine exhaust gas is a complex mixture of particles and gases, including various hydrocarbons and derivatives (e.g. benzene, formaldehyde, toluene and sulfur dioxide), inorganic sulfates and nitrates, metals (including lead and platinum), and polycyclic aromatic hydrocarbons (PAHs).
    2012, the International Agency for Research on Cancer (IARC) listed diesel engine exhaust as a carcinogen, confirmed its carcinogenicity to lung cancer, and reported a positive relationship with bladder cancer.
    , however, there is a lack of research on the relationship between traffic exhaust and gastrointestinal cancer, and a comprehensive study of transport workers' cancer risks is needed.
    , a recent study published in the journal Sci Rep showed that transportation workers are at risk for cancer, such as lung, bronchroid and bladder cancer, from long-term exposure to vehicle engine exhaust.
    researchers used the National Health Insurance Service database to analyze the cancer risks of road transport workers (RTW) exposed to traffic air pollution and motor vehicle engine exhaust, including 594,629 road transport workers, 3,268,312 years of government employees and 62,760,615 years of the working population as a whole.
    researchers defined the history of cancer admitted for the first time in three years as the first case and compared the incidence of cancer, standard incidence (SIR) and 95% CI for road transport workers with other populations.
    results showed that in the liver and liver bile tube cancer (SIR 1.15,95% CI 1.04-1.27), digestive organ cancer (SIR 1.28,95% CI 1.04-1.57), trachea, bronchid In terms of lung cancer (SIR 1.28, 95% CI 1.15-1.43) and bladder cancer (SIR 1.26, 95% CI 1.03-1.52), RTW's cancer incidence is significantly higher than that of government employees and the working population as a whole.
    the use of fixed exposure and dynamic queue definitions over a three-year period, there was no significant reduction in the incidence of other cancers except liver cancer and intra-hepatic bile tube cancer.
    In the first year of fixed exposure, the age-standardized incidence of cancer and 95 percent of the age-standardized incidence and 95 percent confidence interval for road transport workers for each type of cancer risk were high for road transport workers (RTW), including liver cancer, intra-liver biletric cancer, other digestive organ cancer, tracheal cancer, bronchal cancer, lung cancer and bladder cancer.
    the findings could help establish preventive measures against cancer for road transport workers (RTW).
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