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Sci Immunol: Identify special genes that play a key role in the differentiation of natural killer cells!

 Last Update: 2021-04-28
 Source: Internet
 Author: User

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March 19, 2021 // --Recently, a research report titled "transcription factor Bcl11b promotes both canonical and adaptive NK cell differentiation" was published in the international journal Science Immunology , from multiple research institutions in Europe and the United States Through research, scientists have discovered a special gene that plays a key role in the differentiation of natural killer cells.

Science Immunology

Image source: Val Altounian/AAAS

NK cells play an important role in the immune function of the body.

In order for NK cells to perform multiple functions, they must carry multiple types of inhibitory and active receptors.

The researchers found that this process may be controlled by a transcription factor called Bcl11b.

Original source:

Tim D.

Tim D.
Holmes, Ram Vinay Pandey, Eric Y.
Helm, et al.
sciencemag.
org/content/6/57/eabc9801">The transcription factor Bcl11b promotes both canonical and adaptive NK cell differentiation , Science Immunology (2021).
DOI:10.
1126/sciimmunol.
abc9801 sciencemag.
org/content/6/57/eabc9801">The transcription factor Bcl11b promotes both canonical and adaptive NK cell differentiation Science Immunology

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