Sci Adv: Deep sleep is effective in draining waste

January 22, 2021 /--- -- A new study from Northwestern University reaffirms the importance of a good night's sleep.
by examining the brain activity and behavior of fruit flies, the researchers found that deep sleep has an ancient resilience to remove waste from the brain.
this waste may include toxic proteins that can cause neurodegenerative diseases.
. Ravi Allada, senior author of the study at www.pixabay.com, said: "Waste removal is often important for keeping the brain healthy or preventing neurogenic diseases.
may occur during wake and sleep, but waste removal during deep sleep can be greatly enhanced.
" study will be published today in the journal Advanced Journal of Science.
is distinguished professor of neuroscience and head of the Department of Neurobiology at Northwestern University's Weinberg School of Art and Science.
deputy director of the Northwest Center for Sleep and Circadian Biology.
, a postdoctoral researcher at the Alada Laboratory, is the first author of the paper.
although fruit flies look very different from humans, the neurons that control the sleep awakening cycle of fruit flies are strikingly similar to our own.
, fruit flies have become a model organism for studying sleep, circadian rhythms and neurodegenerative diseases.
current study, Allada and his team studied Long Nose Extended Sleep (PES), a deep sleep phase of fruit flies, similar to deep slow-wave sleep in humans.
found that at this stage, fruit flies continue to elongation and retract their nose length (or nose).
pumping may transfer fluid to flies in the kidneys," said Allada, a director of the transplant.
research shows that this helps to remove waste and helps with injury recovery.
Allada's team impaired the deep sleep of fruit flies, which were less able to remove non-metabolic dyes injected into their systems and were more susceptible to trauma."
allada says this study gives us a better understanding of why all living things need sleep.
animals, especially those in the wild, are extremely vulnerable when they fall asleep.
but a growing body of research shows that the benefits of sleep, including important waste removal, far outweigh this increased vulnerability.
found that deep sleep played a role in the waste removal of fruit flies, suggesting that waste removal is an evolutionaryly conservative core function of sleep."
suggests that waste removal may be the sleep function of flies and the common ancestor of humans.
Bioon .com Source: Deep takes sleep out the trash Original link: B. van Alphen el al., "A deep sleep stage in Drosophila with a functional role in waste clearance," Science Advances (2021). advances.sciencemag.org/lookup . . . 1126/sciadv.abc2999