Rotating evaporator shopping tips: do not understand these, advise you not to rush to hand

　　Pharmaceutical Network Technical Article: Rotating evaporators are mainly used for concentration, crystallization, drying, separation and solvent recovery in the pharmaceutical, chemical and biopharmaceutical industries Rotating evaporators on the market vary according to the different models and brands It is understood that most of the domestic prices are cheaper, small generally in the 3000 to more than 10,000 yuan (larger and more expensive), and like the import price is generally more than 10,000 yuan
Industry said that although the imported rotary evaporator price is more expensive than domestic, but in terms of quality is slightly better, most of the laboratory such as schools for sealing is not very high requirements, domestic rotary evaporator can generally be satisfied And some experimental institutions such as scientific research need a strong sealing, otherwise can not ensure the effectiveness of the experiment, such units rely on imported equipment
It is worth mentioning that in recent years, with the continuous development of China's pharmaceutical and biopharmaceutical industry, there are also some rotating evaporator manufacturers for the current needs of laboratory users at home and abroad, the development of a new type of rotary evaporator, instruments equipped with more new safety functions and digital connectivity functions, product stability has been improved, the price is more favorable than imported products
So, in addition to considering price considerations, how should buyers choose a rotary evaporator? Factory technical staff suggested that the purchase of rotary evaporator should first choose the specifications of the rotary evaporator
According to the introduction, the specifications of the rotary evaporator are distinguished by the volume of the evaporation bottle, the size of the required evaporation bottle depends on the amount of the evaporated material In general, 2L, 3L, 5L rotary evaporator is suitable for laboratory small-scale testing, 5L, 10L, 20L is suitable for pilot, 20L, 50L is suitable for pilot and production
Secondly, consider the evaporation rate of the rotary evaporator It is understood that for the same specification of the rotary evaporator, the main factors affecting the evaporation speed of the rotary evaporator are four factors: heating bath temperature, vacuum in the rotary evaporator, condenser cooling medium temperature and evaporation bottle speed
Specifically, in terms of heating bath temperature, the higher the heating bath temperature, the more intense the evaporation of materials However, due to the heat tolerance of the material, the safety of use and energy consumption constraints, the commonly used temperature is 60 degrees C Industry said that the heating bath temperature is moderate, water volatilization rate is low, energy utilization is high
In terms of vacuum degree in the rotary evaporator, the industry recommends a vacuum degree of 95 to 98kPa (absolute pressure 2 to 5kPa), in terms of condenser cooling medium temperature, the relationship between material temperature and vacuum temperature is consistent with the relationship between the material saturation temperature and saturation pressure, in the heating bath temperature and vacuum degree determination, the cooling medium temperature depends on the type of material
In addition, in terms of evaporative bottle speed, the higher the speed of the evaporation bottle, the larger the immersion area of the inner surface of the bottle, the larger the heating area, but at the same time the thickness of the liquid film is also thicker, increasing the temperature difference of heat transfer For materials with different viscosity, there is a speed
After considering the evaporation rate of the rotary evaporator, select the supporting equipment The supporting equipment of the rotary evaporator refers to the vacuum equipment and the cold source equipment
It is recommended in the industry that vacuum pumps be recommended for circulating water vacuum pumps or diaphragm vacuum pumps that are resistant to various solvent severity Optional vacuum controller for a more efficient and controlled distillation process In addition, the cold source equipment is selected according to the temperature and evaporation of the cooling medium.