Risk factors for bleeding after biopsy of lesions in the base area

The risk of bleeding after stereotactic biopsy is generally low, however bleeding in certain special areas can lead to neurological defects in patientsThe base section is highly vascularized, usually the site of cerebral hemorrhage with high blood pressure- Excerpted from the article chapter: Farahmand D, et alClin Neurol Neurosurg2018 Nov; 174:180-184doi: 10.1016/j.clineuro.2018.09.008Epub 2018 Sep 18.) the risk of bleeding afterstereotactic biopsy is generally low, however bleeding in certain special areas can lead to neurological defects in patientsThe base section is highly vascularized, usually the site of cerebral hemorrhage with high blood pressureAnalysis by Dana Farahmand of neurosurgery at Goethe University in Frankfurt, Germany, and others predicted risk factors for bleeding after stereoscopic positioning biopsy in the base area, published online in September 2018 in Clinical And Yaury And Neurosurgerythe study included 514 patients who underwent stereotactic biopsies between January 2012 and January 2017Among them, after the elimination of cysts or bleeding punctures, 63 cases of lesions biopsy in the base sectionCollect data on the age, sex, history of hypertension, intraoperative blood pressure, smoking history, anticoagulant therapy and histopathological diagnosis related to postoperative bleedingAnticoagulant patients stopped taking drugs 7 days before surgeryBiopsies are based on the Leksell frame stereodirectional positioningthe median age of 63 patients was 57 years old, of which 28 were for women (44.4%) and 35 (55.6%) for men The biopsy resulted in a median of 15 tissue samples Histopathological analysis showed that there were 31 cases of glioblastoma (49.2%), 14 cases of lymphoma (22.2%), 3 cases of WHO Grade I astrocytomoma (4.8%), 5 cases of Class II Astrocytom (7.9%), 3 cases of Class III Astrocytom (4.8%) and 3 cases (4.8%) metastatic tumors; 17 patients with postoperative bleeding, of which 6 cases of lesions, 1cm, have a occupatic effect Fisher's exact probability test showed no significant correlation between anticoagulant therapy, sex, smoking, and hypertension, and postoperative bleeding (P 0.05) The Manwhitney test found that systolic pressure, the number of specimens taken, age, etc were not related to postoperative bleeding Bleeding was not related to the pathological type of lesions, and lymphoma had a certain tendency to bleed (P-0.06), but there was no statistical difference concluded that the pathological diagnosis of tumor tissue is a necessary condition for follow-up precision treatment The stereoscopic positioning biopsy of lesions in the base area was safe and reliable, and there was no significant correlation between anticoagulant therapy, smoking, sex and hypertension in patients.