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Reye syndrome – encephalopathy - fatty liver syndrome

 Last Update: 2022-10-02
 Source: Internet
 Author: User

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Brief introduction

Reye syndrome is an acute mitochondrial injury manifested by acute encephalopathy, selective liver impairment, and infiltration of visceral fat, with clinical changes such as encephalopathy and biochemical changes as liver disease

Diagnostic criteria

Children under 18 years of age, present

(1) Acute non-inflammatory encephalopathy (no increase in the number of cerebrospinal fluid cells);

(2) Characteristic liver disease pathology or serum aminotransferase or blood ammonia increase of more than 3 times the normal limit value;

(3) Exclude other diseases

pathogen

Reye syndrome is a mitochondrial disease whose cause is thought to be related

Imaging diagnostics

CT The density of white matter around the ventricles of the brain is significantly reduced, and the ventricles are compressed

It may also present with diffuse cortical and white matter changes, and in the acute phase manifest as a high cortical layered T2WI signal, which can be strengthened; Diffuse layered hypersignal in chronic phase T1WI; At the same time, white matter changes and brain atrophy

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